The Alarming Link Between Muscle Weekness and Brain Health
- AI it News
- Feb 27
- 4 min read
A Neurologist's Perspective

We all know the importance of physical activity for maintaining a healthy heart, managing weight, and boosting mood. But beyond these widely recognized benefits, lies a profound and often overlooked connection between muscle movement and brain health. According to Dr. Kim Johnson Hatchett, a board-certified neurologist, neglecting physical activity, particularly strength training, can have alarming consequences for our cognitive function. In this comprehensive analysis, we delve into Dr. Hatchett's insights and explore the critical role muscle movement plays in preserving brain health and preventing lasting damage.
The Dangerous Habit: Neglecting Physical Activity and Its Impact on the Brain

In a compelling TikTok video, Dr. Hatchett highlights what she considers the most dangerous habit impacting brain health: neglecting physical activity. She emphasizes that muscle weakness is intricately linked to brain function, a connection many people fail to recognize. When patients present with physical weakness or mobility issues, they often don't associate these symptoms with the health of their brain. However, Dr. Hatchett stresses that this disconnect can be detrimental, leading to a decline in cognitive function and an increased risk of neurodegenerative diseases.
The Crucial Role of Nerve Growth Factor (NGF)

Dr. Hatchett explains that neglecting muscle movement deprives the brain of a vital neurotrophic factor called Nerve Growth Factor (NGF). NGF is a critical peptide that plays a crucial role in supporting neurons and myelin, the protective sheath surrounding nerve fibers.
Neurons: These are the fundamental units of the brain responsible for transmitting information throughout the nervous system. NGF promotes the survival, growth, and differentiation of neurons, ensuring optimal brain function.
Myelin: This fatty substance insulates nerve fibers, allowing electrical signals to travel quickly and efficiently. NGF supports the production and maintenance of myelin, which is essential for maintaining cognitive function and preventing neurological disorders.
When we engage in physical activity, particularly strength training, our muscles release NGF, which then travels to the brain and exerts its beneficial effects. By neglecting physical activity, we deprive our brains of this essential nutrient, leading to a decline in neuronal health and myelin integrity.
The Consequences of NGF Deprivation

The consequences of NGF deprivation can be far-reaching and include:
Cognitive Decline: Reduced NGF levels can impair cognitive functions such as memory, learning, and attention. This can manifest as difficulty remembering names, struggling to learn new information, or experiencing a decline in focus and concentration.
Increased Risk of Neurodegenerative Diseases: Studies have shown that decreased NGF levels are associated with an increased risk of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. NGF plays a protective role against these diseases by promoting neuronal survival and preventing the formation of toxic protein aggregates.
Reduced Neuroplasticity: Neuroplasticity refers to the brain's ability to reorganize itself by forming new neural connections throughout life. NGF is crucial for neuroplasticity, allowing the brain to adapt to new experiences and learn new skills. When NGF levels are low, the brain's ability to adapt and learn is diminished.
Impaired Motor Function: NGF is also involved in maintaining motor function by supporting the health of motor neurons, which control muscle movement. Reduced NGF levels can lead to muscle weakness, impaired coordination, and difficulty performing everyday tasks.
Strength Training: A Powerful Tool for Brain Health

Dr. Hatchett emphasizes the importance of strength training for maintaining brain health. Strength training involves using resistance to contract muscles, which in turn stimulates the release of NGF.
Here's how strength training benefits the brain:
Increased NGF Production: As mentioned earlier, strength training stimulates the release of NGF, which supports neuronal health and myelin integrity.
Improved Cerebral Blood Flow: Strength training increases blood flow to the brain, delivering more oxygen and nutrients to neurons. This improved blood flow enhances cognitive function and protects against neurodegenerative diseases.
Enhanced Neuroplasticity: Strength training promotes neuroplasticity, allowing the brain to adapt and learn new skills. This can lead to improvements in memory, learning, and overall cognitive function.
Reduced Inflammation: Chronic inflammation is a major contributor to neurodegenerative diseases. Strength training has been shown to reduce inflammation throughout the body, including the brain, thereby protecting against cognitive decline.
Beyond Strength Training: Other Forms of Physical Activity

While Dr. Hatchett emphasizes the importance of strength training, other forms of physical activity also contribute to brain health. Aerobic exercise, such as running, swimming, and cycling, increases blood flow to the brain and stimulates the release of other neurotrophic factors, such as Brain-Derived Neurotrophic Factor (BDNF). BDNF is similar to NGF in that promotes neuronal survival, growth, and differentiation.
Expert Recommendations for Integrating Physical Activity into Your Routine

Dr. Hatchett and other health experts recommend incorporating regular physical activity into your routine to maintain brain health. Here are some practical tips:
Aim for at least 150 minutes of moderate-intensity aerobic exercise per week. This could include activities such as brisk walking, jogging, swimming, or cycling.
Incorporate strength training exercises into your routine at least twice a week. Focus on exercises that work all major muscle groups, such as squats, lunges, push-ups, and rows.
Find activities that you enjoy and that fit into your lifestyle. If you don't enjoy running, try swimming or cycling. If you don't have time to go to the gym, try doing bodyweight exercises at home.
Start slowly and gradually increase the intensity and duration of your workouts. This will help prevent injuries and make it easier to stick with your routine.
Consult with your doctor before starting any new exercise program, especially if you have any underlying health conditions.
Prioritizing Physical Activity for a Healthy Brain

Dr. Kim Johnson Hatchett's insights highlight the critical connection between muscle movement and brain health. By neglecting physical activity, we deprive our brains of essential neurotrophic factors like NGF, leading to cognitive decline, an increased risk of neurodegenerative diseases, and impaired motor function. Incorporating regular physical activity, particularly strength training, into our routines is essential for maintaining brain health and preventing lasting damage. By prioritizing physical activity, we can safeguard our cognitive function, enhance our quality of life, and reduce our risk of age-related cognitive decline. It's time to recognize that taking care of our bodies is also taking care of our brains, and that movement is not just about physical fitness, but about preserving our cognitive well-being for years to come.
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